However it has been found in other places as well, and occurs in areas where the soil is deficient in selenium. In some cases, discharge from nipples is also prominent. Accumulation of proteins inside the nerve cells in the brain can also cause this condition. The name has been derived from the Latin terms velum, which means palate, cardiac, meaning the heart, and faces, which refers to the face. Tina cruris ringworm of the groin Also known as Jock Itch, tine cruris affects the groin area of the human body. A transvaginal one does not require a full bladder. Electromyogram CMG: A test used for evaluating muscle and nerve function. Is there a simple screening test that can help in the diagnosis of this condition?
Food and Drug Administration today approved Spinraza (nusinersen), the first drug approved to treat children and adults with spinal muscular atrophy (SMA), a rare and often fatal genetic disease affecting muscle strength and movement. Spinraza is an injection administered into the fluid surrounding the spinal cord. There has been a long-standing need for a treatment for spinal muscular atrophy, the most common genetic cause of death in infants, and a disease that can affect people at any stage of life, said Billy Dunn, M.D., director of the Division of Neurology Products in the FDAs Center for Drug Evaluation and Research. As shown by our suggestion to the sponsor to analyze the results of the study earlier than planned, the FDA is committed to assisting with the development and approval of safe and effective drugs for rare diseases and we worked hard to review this application quickly; we could not be more pleased to have the first approved treatment for this debilitating disease. SMA is a hereditary disease that causes weakness and muscle wasting because of the loss of lower motor neurons controlling movement. There is wide variability in age of onset, symptoms and rate of progression. Spinraza is approved for use across the range of spinal muscular atrophy patients. The FDA worked closely with the sponsor during development to help design and implement the analysis upon which this approval was based. The efficacy of Spinraza was demonstrated in a clinical trial in 121 patients with infantile-onset SMA who were diagnosed before 6 months of age and who were less than 7 months old at the time of their first dose. Patients were randomized to receive an injection of Spinraza, into the fluid surrounding the spinal cord, or undergo a mock procedure without drug injection (a skin prick). Twice the number of patients received Spinraza compared to those who underwent the mock procedure.
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