The marked superiority of the 10-day regimen over the 5-day regimen led the independent safety monitoring board overseeing the trial to conclude it prematurely as the primary end point was achieved. “The results of this study clearly show that for treating ear infections in children between 9 and 23 months of age, a 5-day course of antibiotic offers no benefit in terms of adverse events or antibiotic resistance. Though we should be rightly concerned about the emergence of resistance overall for this condition, the benefits of the 10-day regimen greatly outweigh the risks,” said Dr. Hoberman. ### 2QIZGmClS18 Caption: Senior author Dr. Alejandro Hoberman discusses results of the trial studying antibiotic use in young children with ear infections. The study was supported by a contract (HHSN272201000047C) from the National Institute of Allergy and Infectious Diseases and by University of Pittsburgh Clinical and Translational Science Awards (UL1RR024153 and UL1TR000005) from the National Center for Research Resources, now at the National Center for Advancing Translational Sciences, National Institutes of Health. Other authors include Jack L. Paradise, M.D., Howard E. Get More InfoRockette, Ph.D., Diana H.
For the original version including any supplementary images or video, visit https://www.eurekalert.org/pub_releases/2016-12/uops-rad122116.php
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